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@memo72741
Wed, Nov 30, 2022 8:40 PM
Sat, Feb 11, 2023 4:32 PM
1
藥劑生劑
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@memo72741
Fri, Dec 2, 2022 3:06 AM
軟膏劑
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@memo72741
Fri, Dec 2, 2022 3:06 AM
鏡檢
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@memo72741
Fri, Dec 2, 2022 3:06 AM
乳化劑
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@memo72741
Fri, Dec 2, 2022 3:07 AM
雲點 金數
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@memo72741
Wed, Jan 25, 2023 4:24 AM
Sat, Jan 28, 2023 2:36 PM
https://images.plurk.com/4v7S4J1bcjfEEiTHay7CiP.jpg
sc較id深 胰島素 量較多
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@memo72741
Fri, Jan 27, 2023 9:16 AM
Fri, Jan 27, 2023 9:23 AM
https://images.plurk.com/1xqZz1SJcovIWdYOw2gVWM.jpg
非線性
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@memo72741
Fri, Jan 27, 2023 9:24 AM
https://images.plurk.com/AVfisBJZM6YP3L7sMZydp.jpg
Cmax-Cmin
與劑量成正比 τ無關
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@memo72741
Fri, Jan 27, 2023 9:43 AM
Fri, Jan 27, 2023 9:48 AM
https://images.plurk.com/6Lknxv4hwQpf4yWApuywHU.jpg
erythromycin同位素測3A4活性
diagnogreen(ICG)檢視肝循環機能
https://images.plurk.com/3cEWeJIG565Jfax3Ex0ZWT.jpg
MEGX為lidocaine毒代
https://images.plurk.com/1gxNKLCsO3w1kf5ZhmVRcI.jpg
肝腎代謝
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@memo72741
Fri, Jan 27, 2023 9:44 AM
速效劑量取決分佈體積
維持劑量取決清除率
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@memo72741
Fri, Jan 27, 2023 9:47 AM
弱酸OAT 弱鹼OCT
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@memo72741
Fri, Jan 27, 2023 9:47 AM
肌甘酸會被腎小管主動分泌
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@memo72741
Fri, Jan 27, 2023 10:11 AM
Wed, Feb 8, 2023 9:58 AM
https://images.plurk.com/6RAdL1wi4a14Dud82kYpc8.jpg https://images.plurk.com/1dmwa9X59KTwnmRZDLVSj.jpg
酒精
顛茄曼陀羅粉狀浸膏不可碳酸鎂氧化鎂
怡 40 糖
蓄 60
流浸100% 滲鹿
浸膏200～600% 多滲鹿
碘汀 2.5/2.5
複方碘 5/10(KI)

加甘油是浸漬法中避免鞣酸分離
而酏劑中加甘油可以助溶
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@memo72741
Fri, Jan 27, 2023 10:41 AM
Sat, Jan 28, 2023 1:13 PM
https://images.plurk.com/dridUjcPTeDxZqp55Iclo.jpg
8(5)6(5)7(0)6(0)7(0) vwvvw
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@memo72741
Fri, Jan 27, 2023 11:13 AM
Sat, Jan 28, 2023 2:36 PM
https://images.plurk.com/2AJ66nr5nGSPJ2ks9vURkf.jpg https://images.plurk.com/3sjEePHwR4kduHC7pYtCO5.jpg
非ion界活
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@memo72741
Fri, Jan 27, 2023 11:30 AM
Sat, Jan 28, 2023 2:37 PM
https://images.plurk.com/ThXl8LtN5r9s4uNm7BYx1.jpg https://images.plurk.com/Nkui33e8yeFuWejYFXGhA.jpg
非牛頓
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@memo72741
Fri, Jan 27, 2023 11:47 AM
Wed, Feb 8, 2023 9:39 AM
https://images.plurk.com/DtQSEAmE8HDBxdtHvFvOl.jpg
安定性試驗
25/30/40 +35
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@memo72741
Fri, Jan 27, 2023 1:09 PM
Sat, Jan 28, 2023 2:17 PM
https://images.plurk.com/6iDwC3AuEISOlqgicVdrWw.jpg
只有F有分配
擴散大家都有 單位cm2/s
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@memo72741
Fri, Jan 27, 2023 4:08 PM
Sat, Jan 28, 2023 1:10 PM
https://images.plurk.com/5ifaPemDzd58pCgeXtM4ky.jpg
甘油 elixir助溶
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@memo72741
Fri, Jan 27, 2023 5:47 PM
Tue, Jan 31, 2023 2:25 PM
https://images.plurk.com/2mG4f2FR3xCtLXZDZN4VHu.jpg https://images.plurk.com/48YEWSBhqWzWeNPda0NX72.jpg https://images.plurk.com/4GD1rqMu30b9uMZFFsJzDL.jpg https://images.plurk.com/42bARg4v9mVFNmm9kqiC8P.jpg
SiO2溫度不影響
poloxamer酸鹼不影響
plastibase 90度下成膠
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@memo72741
Fri, Jan 27, 2023 5:48 PM
Sat, Jan 28, 2023 2:37 PM
https://images.plurk.com/5PtIKF2rJoCOMJbuwgJhCP.jpg
軟膏劑
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@memo72741
Sat, Jan 28, 2023 7:00 AM
https://images.plurk.com/1gvw1foziqgIkA6tmgXMYx.jpg https://images.plurk.com/6i1FZWzO8XJgEjJih2yQo8.jpg
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@memo72741
Sat, Jan 28, 2023 7:11 AM
Sat, Jan 28, 2023 2:37 PM
https://images.plurk.com/1wM0kBoxAXqbhYQiNvxOQv.jpg
混合 s共融 t毒
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@memo72741
Sat, Jan 28, 2023 7:17 AM
軟膠囊含水較少(6-13%)
硬膠囊(10-15%)
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@memo72741
Sat, Jan 28, 2023 7:18 AM
Sat, Jan 28, 2023 2:19 PM
https://images.plurk.com/62DYNwMURVptNEX102VBOu.jpg
包衣
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@memo72741
Sat, Jan 28, 2023 8:00 AM
Sat, Jan 28, 2023 2:19 PM
https://images.plurk.com/7kakdNS1fChXU45y4Z85DZ.jpg
稀釋劑
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@memo72741
Sat, Jan 28, 2023 10:06 AM
Sat, Jan 28, 2023 2:19 PM
https://images.plurk.com/49202h6WO5LvdjQXH61ax8.jpg
b快 l久
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@memo72741
Sat, Jan 28, 2023 10:12 AM
https://images.plurk.com/5aNOweKAgoUe7e2ki3yosI.jpg
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@memo72741
Sat, Jan 28, 2023 10:20 AM
Sat, Jan 28, 2023 2:38 PM
https://images.plurk.com/4LTpHKSlugcxIExZ5n6MQR.jpg
主動被動
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@memo72741
Sat, Jan 28, 2023 10:23 AM
Sat, Jan 28, 2023 2:38 PM
https://images.plurk.com/7f8jUBcSLGD2gXtqAfrKAu.jpg
培養基
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@memo72741
Sat, Jan 28, 2023 10:42 AM
Sat, Jan 28, 2023 2:38 PM
https://images.plurk.com/Pob69KSpzRptnYu7xiZut.jpg
防腐
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@memo72741
Sat, Jan 28, 2023 10:42 AM
26/47
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@memo72741
Sat, Jan 28, 2023 10:43 AM
Wed, Feb 8, 2023 1:39 PM
密度小→大
色淺→深
熔點高→低
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@memo72741
Sat, Jan 28, 2023 10:45 AM
Sat, Jan 28, 2023 2:38 PM
https://images.plurk.com/35CRZlaMrSLtqybWK11hCj.jpg
poloxamer
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@memo72741
Sat, Jan 28, 2023 1:20 PM
注射用水不需無菌→美
0.45→中
只蒸餾→歐
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@memo72741
Sat, Jan 28, 2023 1:27 PM
酸 sodium metabisulfatr Na2S2O5
中 sodium bisulfate NaHSO3
鹼 sodium sulfate Na2SO3
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@memo72741
Sat, Jan 28, 2023 1:32 PM
Sat, Jan 28, 2023 1:35 PM
高壓蒸氣(蛋凝) 蒸氣出口 壓x時=300 溫=壓+106
乾熱 160～170 2～4hr→除熱源則250 30～45min
氣體(烷化改變代謝)
放射(突變) EtO ClO2

濕熱無枯草
乾熱無嗜熱
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@memo72741
Sat, Jan 28, 2023 1:40 PM
林格 NaCl+KCl+CaCl2
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@memo72741
Sat, Jan 28, 2023 1:41 PM
Sat, Jan 28, 2023 1:42 PM
https://images.plurk.com/5BX2VZuXH478HYU3cB0aFt.jpg
化學方法 強鹼 氧化
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@memo72741
Sat, Jan 28, 2023 1:49 PM
Sat, Jan 28, 2023 1:56 PM
過篩 算數平均 50-5000μm
顯微鏡 投影 0.5-100μm(光)
氣體 容積/表面平均 穿透→氣流/比表/Fisher/5～100 吸附→0.005(小)～20
康特(coulter) 電荷
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@memo72741
Sat, Jan 28, 2023 1:51 PM
Sat, Jan 28, 2023 1:53 PM
眼用 高壓蒸氣 121 15min 熱不安定→0.22
10μl 15-25cps 0.6-2% 7.4
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@memo72741
Sat, Jan 28, 2023 1:58 PM
Sat, Jan 28, 2023 7:39 PM
https://images.plurk.com/6nTNrH7CfDuudgFw1RMQPx.jpg
https://images.plurk.com/HBIyFLzgQSRBs83jDlyBP.jpg
https://images.plurk.com/12QnMJNhqDKb9tZ4mmJiA0.jpg
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@memo72741
Sat, Jan 28, 2023 2:11 PM
篩網 400 38μm
膠囊 (1) 0.32gm aspirin (5) 0.13ml水
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@memo72741
Sat, Jan 28, 2023 2:14 PM
https://images.plurk.com/6PWlX0flssB7enHbcFwBf5.jpg
✦✧✦✧
@memo72741
Sat, Jan 28, 2023 2:29 PM
https://images.plurk.com/45Y33N5R1JJCXblCRcaEfb.jpg https://images.plurk.com/3saJtiGIIdSjJdvx2qqnD1.jpg
✦✧✦✧
@memo72741
Sat, Jan 28, 2023 2:35 PM
top spray 不適用sustained release
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@memo72741
Sat, Jan 28, 2023 2:43 PM
膠體 20A～1μ
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@memo72741
Sat, Jan 28, 2023 4:22 PM
https://images.plurk.com/52Y357ms3fVcN6Lc678SCb.jpg
兔子
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@memo72741
Sat, Jan 28, 2023 4:34 PM
Sat, Jan 28, 2023 4:35 PM
2C19在小腸
erythromycin, omeprazole避免胃酸破壞
✦✧✦✧
@memo72741
Sat, Jan 28, 2023 4:46 PM
Sat, Jan 28, 2023 4:59 PM
極難溶 溶蝕
可溶 滲透
惰性 擴散 滲透
親水 溶蝕
HPMC 緩釋 溶蝕
https://images.plurk.com/4yGwry3IYV6ysECw1YaMC5.jpg
✦✧✦✧
@memo72741
Sat, Jan 28, 2023 5:18 PM
https://images.plurk.com/GNGqKzWGw3l7mJdjPEiFK.jpg
flip flop
✦✧✦✧
@memo72741
Sat, Jan 28, 2023 6:28 PM
https://images.plurk.com/JGNotIxQddHY0ukvrTg3O.jpg
✦✧✦✧
@memo72741
Tue, Jan 31, 2023 9:54 AM
Tue, Jan 31, 2023 9:55 AM
SLS帶酸根(陰ion) 鹼性下作用
明膠A 酸性下解離作用
明膠B 鹼性下解離作用
✦✧✦✧
@memo72741
Tue, Jan 31, 2023 10:47 AM
Wed, Feb 8, 2023 10:27 AM
https://images.plurk.com/6pseQyzG07KN6f92AiC4CH.jpg
脂魚4 其他2
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@memo72741
Tue, Jan 31, 2023 10:52 AM
dosage replacement=藥換賦
✦✧✦✧
@memo72741
Tue, Jan 31, 2023 2:30 PM
Tue, Jan 31, 2023 2:32 PM
PEG+水溶液硬化→18醇
與苯甲酸混合→126 hexanetriol增加相容
✦✧✦✧
@memo72741
Tue, Jan 31, 2023 2:44 PM
https://images.plurk.com/7N1iqx9Q5FXXnDuQGOFzWQ.jpg
✦✧✦✧
@memo72741
Tue, Jan 31, 2023 3:01 PM
樟腦製劑使用助研法（Pulverization by intervention），一般使用乙醇、乙醚、氯仿或其他揮發性溶劑當助研劑
✦✧✦✧
@memo72741
Tue, Jan 31, 2023 6:39 PM
https://images.plurk.com/36DAMabqE6bRxvTV0SimCn.jpg
✦✧✦✧
@memo72741
Tue, Jan 31, 2023 7:07 PM
https://images.plurk.com/458geMYAANAPIURsYL1y15.png
✦✧✦✧
@memo72741
Tue, Jan 31, 2023 7:14 PM
https://images.plurk.com/4uisqOqUqRXsMrrSM2wm1k.png
✦✧✦✧
@memo72741
Tue, Jan 31, 2023 7:51 PM
https://images.plurk.com/5oA43Jk5IhB7fF1bBBn1HO.png
✦✧✦✧
@memo72741
Wed, Feb 1, 2023 1:07 AM
https://images.plurk.com/2B1Kj5JDez7dW0QLgPxOsH.jpg
✦✧✦✧
@memo72741
Fri, Feb 3, 2023 5:11 PM
時間依賴 vancomycin digoxin
✦✧✦✧
@memo72741
Wed, Feb 8, 2023 9:45 AM
https://images.plurk.com/41unP4VGwfMipibXD0BqVU.jpg https://images.plurk.com/4JsJHc67KcUFa8Hry1KQZ.jpg
✦✧✦✧
@memo72741
Wed, Feb 8, 2023 10:42 AM
Wed, Feb 8, 2023 10:44 AM
https://images.plurk.com/7vY2qQQtVWh6jOCHRMixfD.jpg
次世代 動力學
多段 顆粒
馬普爾？
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@memo72741
Wed, Feb 8, 2023 10:51 AM
55 氣
✦✧✦✧
@memo72741
Wed, Feb 8, 2023 1:20 PM
親水軟膏 白軟
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@memo72741
Wed, Feb 8, 2023 1:34 PM
可可脂--->捏和法 壓製法 熔和法

甘油明膠栓劑--->熔和法

PEG--->熔和法
✦✧✦✧
@memo72741
Wed, Feb 8, 2023 1:41 PM
DR=賦/藥，藥重xDR=賦重
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@memo72741
Wed, Feb 8, 2023 2:14 PM
Wed, Feb 8, 2023 2:26 PM
https://images.plurk.com/1xGcZ5HMv8qH6BJN12yy0m.jpg
為防止明膠於製造硬膠囊殼時分解，可加入 0.15%之SO2
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@memo72741
Wed, Feb 8, 2023 2:55 PM
Wed, Feb 8, 2023 3:01 PM
https://images.plurk.com/5KB2fMOg4FEa6LAoUxmPWc.jpg https://images.plurk.com/42sBslDVc7Ne84jFFWIdyT.jpg https://images.plurk.com/4nkmxEvsflSYtQOActspSG.jpg
康特 體積
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@memo72741
Thu, Feb 9, 2023 1:21 AM
https://images.plurk.com/6WnR2y2jYLMd1zZy3uocI.jpg
✦✧✦✧
@memo72741
Thu, Feb 9, 2023 1:26 AM
https://images.plurk.com/5nLvwiTr1a5cihTowT1LTy.jpg
✦✧✦✧
@memo72741
Thu, Feb 9, 2023 1:41 AM
Thu, Feb 9, 2023 1:45 AM
https://images.plurk.com/4yOl5eWfMi76fxcOl8yjQ8.jpg
✦✧✦✧
@memo72741
Thu, Feb 9, 2023 2:14 AM
https://images.plurk.com/6nrO53grEnXXYG3A9qMOAa.jpg
✦✧✦✧
@memo72741
Thu, Feb 9, 2023 2:19 AM
https://images.plurk.com/2ijNAPLKFI0GY7Nplouh2p.jpg https://images.plurk.com/5NNmkPFX6kiPyT2ApaI0hy.jpg
✦✧✦✧
@memo72741
Thu, Feb 9, 2023 2:29 AM
https://images.plurk.com/6sgDMoXT92hQqA5cEW6saA.jpg
✦✧✦✧
@memo72741
Thu, Feb 9, 2023 2:35 AM
https://images.plurk.com/6uqEsnj1iWgT3Rv10yZ6ee.jpg
✦✧✦✧
@memo72741
Thu, Feb 9, 2023 2:39 AM
https://images.plurk.com/9onuQRknW8KzHHC6VUYBe.jpg
✦✧✦✧
@memo72741
Thu, Feb 9, 2023 2:45 AM
https://images.plurk.com/3zaaU2uUdANQ0VA59rQp6C.jpg
✦✧✦✧
@memo72741
Thu, Feb 9, 2023 3:00 AM
tmax公式
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@memo72741
Thu, Feb 9, 2023 3:02 AM
https://images.plurk.com/7mHDvy6cV4Xo2oOmh1Ssel.jpg
✦✧✦✧
@memo72741
Thu, Feb 9, 2023 3:12 AM
Thu, Feb 9, 2023 3:15 AM
https://images.plurk.com/2ytfJIhNKND1j1Keay5N95.jpg
min=初
max=2初
✦✧✦✧
@memo72741
Thu, Feb 9, 2023 3:21 AM
Thu, Feb 9, 2023 3:23 AM
AUC受k影響
T max不變
✦✧✦✧
@memo72741
Thu, Feb 9, 2023 3:35 AM
https://images.plurk.com/2lEP81t8zNLuHrNsvFnuIK.jpg
✦✧✦✧
@memo72741
Thu, Feb 9, 2023 3:45 AM
https://images.plurk.com/4keVFvlnn6XWb7n25yrJcQ.jpg
載入新的回覆