bio-psy_note

Multiple sclerosis - Symptoms and causes

in CNS mylin delay and stop
sym.: numbness, weakness, tremor
Tingling or pain in parts of your body

20-40J, female, high latitude, genetic and envi.

Epilepsy

Seizure episodes are a result of excessive electrical discharges in a group of brain cells.

partial e. : (1)partial non-cons., (2)complex affect cons., doing the thing repeat (in temporal lobe)
generalized e. : (1)small non-cons, stop talking, moving. (2) large cons., dauert 1-3 minuten,.(severe)

H.M patient, 1953, remove both sides medial temporal lobe, effective for the sym. of epilepsy, but LTM and the Anterograde Amnesia

What is the Digit Span test?

PEBL Corsi Block-tapping Task

Korsakoff's Syndrome | Causes (ex. Alcoholism), Symp...

detail

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NMDA receptor (glutamate)
(1) learning: raise NMDA.R open the Ca2+ channel
(2)if there is sb. get cerebral ischemia, ischemia→EPSPs release Gultamate→NMDA.R↑→Na+, Ca2+↑ (repeat again and again)

LTP
(1)learning: NMDA.R
(2)maintainning: changes the stru. Astrocytes can help
(3)recall: Nitric oxide feedback→ more neurotransmitters

Hippocampus: spatial location
　place cells
　engram cells
　concept cells
entorhinal cortex:
　grid cells (x, y)
　head-direction cells
　border cells
Medial temporal lobe: object recognition