Whenever there is an accumulation of metabolically-produced acids, the body attempts to neutralize those acids to maintain a constant acid-base balance. This neutralizing is achieved by using up various "buffering" compounds in the blood stream, to bind the acids, disallowing them from contributing to more acidity.
About half of these buffering compounds come from HCO3, and the other half from plasma and red blood cell proteins and phosphates. The words "base deficit" and "base excess" are equivalent and are generally used interchangeably. The only difference is that base deficit is expressed as a positive number and base excess is expressed as a negative number.
1. 定義為"偏離正常緩衝能力(buffering availability)的程度"
2. 算法: BE= {pH-[7.4-(PCO2-40)/200]}x100
->是由measured pH和PaCO2來計算BE
3. BE能評估"非呼吸性酸鹼失衡"之程度，反映HCO3之濃度
->if BE>+/-10mmol/L則表示明顯不正常
->負(-)為"代謝性酸中毒"
->正(+)為"代謝性鹼中毒"
This neutralizing is achieved by using up various "buffering" compounds in the blood stream, to bind the acids, disallowing them from contributing to more acidity.
The words "base deficit" and "base excess" are equivalent and are generally used interchangeably. The only difference is that base deficit is expressed as a positive number and base excess is expressed as a negative number.
這種中和是通過在血流中使用各種“緩衝”化合物來實現的，以結合酸，使它們不再有助於提高酸度。
這些緩衝化合物中約有一半來自HCO3，另一半來自血漿和紅細胞蛋白質和磷酸鹽。
“鹼缺乏”和“鹼基過量”這兩個詞是等同的，通常可互換使用。唯一的區別是鹼缺乏表示為正數，鹼基過量表示為負數。