of those, Ganta is the only one who shows physical attraction in canon, so he might smash if the situation was right? but it's pretty unlikely he's done anything yet, he's 14
I will say that we don't know exactly what happened between Ryouko and her ex but since he was abusive I don't really want to speculate much on it. I believe they did not go that far physically
also despite Torako's canon being an ecchi manga, I don't think we actually have any canon on her relationship history or sexual experience. it feels like the kind of thing that would come up
Sakura has a kinda-sorta boyfriend so one can speculate, but she's so buttoned-up and he's in the hospital and they're not even formally together. I don't think too much has happened
of the rest... I also play exactly one canonical virgin which is LBH at canonpoint. he's also the only one who has sex on-page if I'm counting the entire canon
(e: vague talk of underage sexuality in plurk, nothing detailed)
Who in Smash has Smashed? (Corrections)